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Rood Synephrine HCL budada (5985-28-4)

Synephrine budada HCL waa kiimiko caadi ah oo kiimiko ah oo laga helo kiimiko ah oo laga helay dhirta oo laga soo saaro si loogu isticmaalo kaalmo dheeri ah ......


Status: Wax soosaarka Mass
Unugga: 25kg / Drum
Capacity: 1450kg / bishii

Description

Qalabka Hilibka ah ee loo yaqaan "RH Synphrine HCL" (5985-28-4)

Qalabka Hilibka ee Roodhada HCL (5985-28-4)

Product Name Rood Synephrine budada HCL
Magaca Kiimikada Synephrine hydrochloride; 5985-28-4; 4- (1-Hydroxy-2- (methylamino) ethyl phenol, hydrochloride;
brand NAme Yocon
Fasalka Daroogada Fat ayaa lumay
CAS Number 5985-28-4
InChikey COTCEGYSNTWJQV-UHFFFAOYSA-N
Molecular Formula C9H14ClNO2
Molecular Wsideed 203.666 g / mol
Monoisotopic Mass 203.071 g / mol
barafku Psaliid 147-150 ° C
Boiling Point 341.10 ° C. @ 760.00 mm Hg (est)
Biological Life-Life Taariikhda lama heli karo
Color Caddaan cad oo budada ah
SOlubility Taariikhda lama heli karo
Storage Temperature qaboojiyaha
Application Takhasuska maaddooyinka dufanka leh ee ugu waxtarsan

Raw Synephrine hcl budada (5985-28-4) Sharaxaad

Raw Synephrine waa budada HCL waa kiimiko caadi ah oo kiimiko ah oo laga helo kiimikada oo laga helay dhirta oo loo soo saaro si loogu isticmaalo buuxinta. Synephrine waxaa mararka qaarkood loogu yeeraa 'orange orange' sababtoo ah waxaa laga soo qaatay liisas yar. Xaqiiqda dhabta ah, waxaa dabiici ah laga helaa cirifka liinta, taas oo ah sababta loogu yaqaano sida orantada qadhaadh. Orange beryahan ah ayaa hadda loo isticmaalaa arrimo lamid ah oo la mid ah iyo sidoo kale qaar ka mid ah dhibaatooyinka casriga ah ee maanta la mid ah miisaanka lumay iyo sida gargaarka ah ee la dagaallanka cagaha ciyaaraha fudud. waa mid ka mid ah xayawaanka ugu weyn ee liinta oranaya oo loo maleeyaa inuu yahay aasaaska tayada warshadda Raw Synephrine HCL, argagax leh maaddooyinka gubanaya ee ugu fiican. Xayawaanka waxaa laga helaa liimeyaal, markaad haysan karto waxay ka faa'iideysanayaan dhamaan siyaabo kala duwan.

Maaddaama ay ka kooban tahay cuntada dheeraadka ah, budada HCL ayaa laga yaabaa inay u badantahay inta badan koritaanka marka loo isticmaalo si habboon. Si kastaba ha noqotee, waxaa jira waxyaalo saameyn xun oo khafiif ah oo ka dhexjira dadka isticmaala kuwaas oo qaadanaya qolka synephrine. Synephrine waa kicin, sidaas darteed waa muhiim in la bilaabo qiyaas yar oo lagu qiimeeyo dulqaad. Qalliinka HCL ee xad-dhaafka ah wuxuu keeni karaa in si deg-deg ah kor ugu kaco dhiig-karka, qallalka wadnaha, maqaarka maqaarka, fadhiga, degenaanshaha, kacsanaanta, dhibaatooyinka neef-mareenka, dawakhaad, madax-xanuun, murqaha, sonkorta dhiiga oo hoos u-dhacda iyo isku-dhafka sonkorta dhiigga, xanuunka caloosha, lallabada iyo shubanka, gaar ahaan la socda kiciyeyaasha kale.

Synephrine hcl budada (5985-28-4) Mashruuca Hawlaha

Dhibaatooyinka wadnaha iyo xididada ee ku dhaca laf-dhabarka waxay la xiriiraan dib-u-qaadista adrenergic. Guud ahaan, marka leysku xiro xayiraadaha α-adrenergic, xuubka xajinta ayaa dhacda, iyo marka la qabsanayo xarumaha xayiraadaha ah ee xinjirowga-adrenergic, qandhada wadnaha iyo kordhinta natiijada garaaca wadnaha. Cilmi-baaristu waxay muujinaysaa in budhcadda hcl-ga ee xermiska ah ay ku xidhan tahay xayawaanka-adrenergic reseptors, taasoo keentay in korodhka awoodda jidhka ee jebinta dufanka. Xakamaynta xayawaanka β1-adrenergic ma saameyneyso xaddiga wadnaha ama cadaadiska dhiigga. Mar labaad, sababtoo ah synephrine waxay muujinaysaa wax yar ama aan ku xirneyn xakamaynta α3-, α3-, β1-, iyo β2-adrenergic reseptors iyo uma muuqato in ay qaadaan saameynta aan tooska ahayn ee adrenergic, saameynta wadnaha, sida kordhinta wadnaha garaaca iyo cadaadiska dhiigga waayo-aragnimooyinka qiyaasta la isticmaalo, oo ka duwan noocyo kale oo ah phenylethylamine iyo phenylpropanolamine derivatives. Isbeddelada dhismaha yaryar waxay keenaan kala duwanaansho weyn oo ku yimaada soo qaadashada adrenergic iyo kaddibna awooda lagu abuuro saameyno wadnaha.

Kiniiniga "Synephrine" wuxuu sidoo kale kordhiyaa isticmaalka jidhka ee karbohidraatka adigoo soo saaraya tamar badan ATP.49-52 Wuxuu fududeeyaa kor u qaadida gulukooska ee unugyada muruqyada, iyo sidoo kale glycogenolysis, gluconeogenesis, glycolysis, iyo oksijiin. Ku lug lahaanshaha calcium iyio iyo cAMP oo leh qaboojiyeyaasha adrenergic ayaa lagu muujiyey inay ku lug leeyihiin geeddi-socodka hab-dhaqameedkan, taas oo muujinaysa ka qayb-qaadashada habab badan.

Marka laga soo tago, isticmaalka budada sephromine ee Synephrine ayaa horjoogsanaya waxqabadka NF-kB. Maaddadani waxay fure u tahay in ay keento xanuunka inflammatory sida neefta. Isticmaalka kalluunka sunta "Synephrine" ayaa sidoo kale lagu ogaadey in uu saameeyo ficilka hoormoonka eotaxin-1 inta badan. Tani waxay ka hortagtaa dhaqdhaqaaqa eosinophil oo ah aag la yiraahdo.

Inkasta oo aan si fiican loo xaqiijin iyada oo loo marayo tijaabooyinka, isticmaalka budada hareeraha ee "Synephrine hcl" ayaa la ogaaday in la joojiyo tallaabada acetylcholinesterase. Kiimikadaan waxaa loo yaqaanaa inay keento cudurka Alzheimers.

Faa'iidooyinka ee Sefafiin hcl budada (5985-28-4)

  • Synephrine hcl miisaan khasaare ah
  • Synephrine hcl waxay caawiyaan cunto xumida
  • Synephrine hcl waxay kordhisaa guluukooska muruqa muruqa
  • Synephrine hcl waxay caawisaa qalabka glycogenesis
  • Cudurka macaanka ee 'hypothermia' wuxuu ka caawiyaa diabeteska
  • Synephrine hcl waxay hagaajinaysaa dheefshiidka
  • Synephrine hcl waxay yareyneysaa dareenka qalliinka ka hor
  • Synephrine hcl waxay hagaajinaysaa dabeecadaha iyo heerarka tamarta
  • Synephrine hcl waxay gacan ka geystaan ​​ilaalinta bakteeriyada waxyeellada leh
  • Synephrine hcl waxay caawisaa yaraynta xanuunka

Cinwaanka lagu taliyey hcl budada (5985-28-4)

Qiyaasta daawada loo isticmaalo ee ugu badan ee loo isticmaalo qiyaastii waa xNUMXmg maalintii. Tani waxaa loo tixgeliyaa inay tahay qiyaasta ku filan oo lagu gaari karo miisaan lumis. Si kastaba ha ahaatee, xaddiga lagu taliyey in xitaa dadka isticmaala shardi waa in aysan dhaafin waa 100mg maalintiiba. Wax kasta oo ka sarreeya calaamaddan waxaa loo tixgeliyaa in ay sun yihiin oo qofku halis ugu jiro inuu ku dhaco qulqulka saameynaha dhimashada ee la xidhiidha isticmaalka kiciyaha. Waxaa lagugula talinayaa, inaad bilowdid, 200 ilaa 10mg si loo hubiyo in budada sephrine-ka ee hudheelka ah ay si dhib leh uula socdaan jidhkaaga. Kadib qaadashada qiyaasta bilowga ah, waa inaad qaadatid wakhti aad ku qiimeyso jawaabta jidhka ee dheeraadka ah. Haddii ay dhamaantiis tahay, qiyaasta labaad ee ku saabsan 20mg ayaa lagu dari karaa laba saacadood ka dib. Marka la eego, mudada ugu yar ee qiyaasta ah waa qaadashada budada Synephrine hcl hal mar labadii saacadoodba mar.

Dhibaatooyinka ay keento ee Sefafiin hcl budada (5985-28-4)

Isticmaalka synephrine waxaa sidoo kale weheliya saameyno sida daawooyinka kale. Marka hal labbo oo lab ah la isticmaalo isticmaalka synephrine hcl oo leh kaafeyn. sidoo kale waxay la yimaadaan waxyeelo qaar. Waxyaabaha soo socda ayaa ah waxyeelo caadi ah:

  • Cadaadis dhiig oo sarreeya.
  • Cudurka wadnaha.
  • Wadne garaacsanaan la'aan.
  • Dhimashada haddii loo isticmaalo qiyaasta sare ee qaliinka ka hor.
  • Maqalka / maskaxda
  • Isku-buufinta iyo dhiig-xinjirowga
  • Dhibaatooyinka wadnaha oo wadnaha ah (fayruuska hurgumeysan)
  • Hoos u dhac ku yimaada xajmiga muruqa (rhabdomyolysis)
  • Kelyaha oo shaqo la'aan ah
  • Xinjiro dhiig
  • Dhaawaca dareemayaasha waxaa sabab u ah cadaadiska kordhaya ee muruqyada (qaybta laf dhabarka ah)
  • Xanuunka laabta (angina angina)
  • Stroke

U DIYAAR-GARASHADA iyo kala-tagga:

Qalabkan waxaa loo iibiyaa Adeegsiga Cilmi-baarista Kaliya. Shuruuda Iibka ayaa la Codeynayaa. Loogu talagalay Isticmaalidda Aadanaha, ama Daawooyinka, Caafimaadka Xoolaha, ama Isticmaalka Guryaha.


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Tixraacyada iyo xaashiyadaha alaabada

Sidee Loogu Dhaawacmaa Heflin HCL?

tixraacyada

  1. Akhlaghi, M., Shabanian, G., Rafieian-Kopaei, M., Parvin, N., Saadat, M., iyo Akhlaghi, M. Citrus aurantium ubaxa iyo walaaca preoperative. Rev Bras.Anestesiol. 2011; 61 (6): 702-712.
  2. Bent, S., Padula, A., iyo Neuhaus, J. Badbaadada iyo waxtarka aaladda liinta ee murgacashada miisaanka. Am.J.Cardiol. 11-15-2004; 94 (10): 1359-1361
  3. Campbell-Tofte, JI, Molgaard, P., Josefsen, K., Abdallah, Z., Hansen, SH, Cornett, C., Mu, H., Richter, EA, Petersen, HW, Norregaard, JC, iyo Winther, K. Daraasad kiliin ah oo laba-indho-indho-indho-indheeye ah oo ku saabsan waxtarka nabadgelyada iyo ka-hor-imaadka macaanka ee Rauvolfia-Citrus, sida lagu isticmaalo daawada dhaqameed ee Nijeryaanka. J ootofarmacol. 1-27-2011; 133 (2): 402-411.
  4. R. Costa, MBA Glória, oo ku jirta Ansixinta Daraasaadka Cuntada iyo Nafaqada (Wargeyska Labaad), 2003
  5. Ghanim H, Sai CL, Upadhyay M. et al. Casiir ama orange ayaa nuujineysa saameynta proinflammatory ee cuntada dufanka sare, carbohydrate-ka iyo waxay ka hortagtaa kordhinta endotoxin iyo muujinta qaabka loo yaqaan 'toll-like reseptor'. Amer J Clin Nutr. 2010, 91: 940-949
  6. Stohs SJ. Qiimaynta warbixinnada xaaladaha xun ee la xiriira Citrus aurantium(orange bitter) laga bilaabo Abriil 2004 illaa Oktoobar 2009.
  7. Dragull K, Breksa AP, Cain B. Synephrine ee cabitaanka casiirka mansabka Satsuma (Citrus unshiuMarcovitch). J. Agric.Food Chem. 2008, 56: 8874-8878
  8. Roman MC, Betz JM, Hildreth J. Go'aaminta synephrine ee qalabka cagaaran qorraxda, dabeecadaha, iyo dheellitirka cuntada oo laga helo kromatografi dareer leh ogaanshaha ultraviolet: hal shaybaarka oo keliya. J Amer Org Anal Chemists Int. 2007, 90: 68-81
  9. Mercolini L, Mandrioli R, Trere T. et al. Falanqaynta cabbirka CE-ga ee aminjirrada adrenergic ee qaybo kala duwan Citrus aurantiummiro iyo cunto dheellitiran. J Sep Sci. 2010, 32: 1-8
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Shangke Kiimikadu waa shirkad tayo sare leh oo ku takhasusay dhexdhexaadinta firfircoon ee daawada (APIs). Si loo xakameeyo tayada inta lagu jiro wax soo saarka, tiro badan oo xirfadlayaal khibrad leh, qalab wax soosaaraya iyo shaybaarrada ayaa ugu muhiimsan.

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