Lithium orotate (5266-20-6)

March 9, 2020

Lithium orotate waa cusbo ka kooban lithium (bir macdanta alkali ah) iyo orotic acid (xarun si dabiici ah looga sameeyay jirka) …….


Status: Wax soosaarka Mass
Isuduwis iyo Haboonaanta La Isticmaali karo
Capacity: 1277kg / bishii

Lithium orotate (5266-20-6) fiidiyaha

Lithium orotate (5266-20-6) sooc

Product Name Lithium orotate
Magaca Kiimikada lithium acid-lithium cusbada monohydrate ; lithium; 2,4-dioxo-1H-pyrimidine-6-carboxylate; Lithiiorotasmonohydricum; UNII-L2N7Z24B30;
CAS Number 5266-20-6
InChikey IZJGDPULXXNWJP-UHFFFAOYSA-M
dhoolla caddayntaada [Li +]. C1 = C (NC (= O) NC1 = O) C (= O) [O-]
Formula kelli C5H5LiN2O5
Miisaanka kelli 180.04
Monoisotopic Mass 162.025285 g / mol
Dhibicda Biyaha ≥300 ° C
Boiling Point N / A
Color cad
Codsiga Liinta-lithium-ka-iibinta ee loo yaqaan 'verhi the-counter lithium orotate' waxaa loo dallacsiiyay inay tahay kaabitaan caafimaad oo loogu isticmaalo il-biyo hoose oo lithium ah; Waxaa loo isticmaali karaa qaddarka hoose ee lithium orotate ee daaweynta khamriga, xanuunka dhanjafka, iyo niyad-jabka la xiriira cudurka laba-cirifoodka.

Waa maxay Lithium orotate?

Lithium orotate waa cusbo ka kooban lithium (bir macdanta alkali ah) iyo orotic acid (xarun si dabiici ah looga sameeyay jirka). Xeradan, lithium-ka ayaa ah mid aan si qasab ah ugu xidhnayn ion orotate, halkii laga isticmaali lahaa kaarboon ama ion kale, iyo sida cusbada kale, ayaa loo kala daadiyaa xalka si loo soo saaro ion lithium bilaash ah. Intooda ugu badan ee laga helo lithium orotate waxaa la siiyaa qaab kaabeyaasha cuntada ah, oo lagu qiyaaso inay tahay daaweyn dabiici ah oo loogu talagalay dhibaatooyinka caafimaad ee kala duwan ee maskaxda, in kasta oo si kooban loo baaray inta u dhaxaysa 1973-1986 si loo daweeyo xaaladaha caafimaad qaarkood, sida khamriga iyo cudurka Alzheimer. .

Daawooyinka kale, lithium orotate waxay beddeli kartaa lithium waxaana loo isticmaali karaa in lagu daaweeyo lagana hortago marxaladaha galmada ee dadka qaba cudurka dhimirka. Lithium ayaa la sheegay inay daaweyso kana hortagayso marxaladaha manic-ga iyadoo la yareynayo waxqabadka maskaxda ee aan caadiga ahayn.

In kasta oo aashitada loo yaqaan 'otic acid' mararka qaarkood loo yaqaan 'Vitamin B13', dhab ahaan looma tixgeliyo fiitamiin. Jirka bini’aadamka, aashitada loo yaqaan 'otic acid' waxaa laga soo saari karaa shey-barooyinka laga helo xiidmaha. Ka sokow, waxay sidoo kale leedahay adeegyo kale oo wanaagsan oo maskaxda iyo jidhka ah.

Sidee bay Lithium orotate u shaqaysaa?

Cusbada lithium-ka ee acid acid (lithium orotate) waxay hagaajineysaa saameynta gaarka ah ee lithium-badan oo laab laab ah iyadoo la kordhinayo ka faa'ideysiga biohium-ka. Orotates-ka ayaa u dhoofiya lithium-ka xuubabka xuubka mitochondria, lysosomes iyo unugyada glia. Lithium orotate wuxuu xasiliyaa xuubka lysosomal wuxuuna ka hortagaa falceliska enzyme-ka ee mas'uul ka ah yaraanta sodium iyo fuuqbaxa ee cusbada kale ee loo yaqaan 'lithium salt'.

Faa'iidooyinka Lithium orotate

Lithium orotate waxaa loo isticmaalaa in lagu daaweeyo cudurka foosha xun ama niyad jab ee bukaanada qaba cudurka laba-cirifoodka, iyo sidoo kale in laga hortago soo noqnoqoshada dhacdooyinka manic. Waxay sidoo kale faa'iido u yeelan kartaa kuwa walwal culus ka qaba PTSD waxayna gacan ka geysan karaan xasilloonida niyadda ee weerarada argagaxa.

Bartamihii 80-meeyadii daraasad aalkolo ayaa la sameeyay oo lagu ogaadey in daaweynta Lithium orotate maalin kasta ay ka caawisay dadka khamriga ah safarkooda inay joojiyaan khamriga. Kuwa ka cabanaya OCD iyo cilado maskaxeed ayaa ka faa'iidaysan kara. Intaa waxaa sii dheer, Lithium orotate kaliya ma isticmaasho la-talinta daaweynta, laakiin waxay sidoo kale kaa caawin kartaa la qabsiga muddada hawsha baxnaaninta.

Sidoo kale, Lithium orotate sidoo kale waxay door wanaagsan ka ciyaaraysaa ilaalinta maskaxda. Lithium orotate wuxuu ilaaliyaa maskaxda isagoo ka hortagaya luminta unugyada maskaxda wuxuuna soo saaraa unugyada maskaxda ee cusub. Waxay muujisay inay wax ka beddesho cudurka Parkinson, cudurka Alzheimers iyo waallida. Daraasadaha xayawaanka ee lithium orotate waxay muujiyeen horumarin dhaawacyada maskaxda iyo istaroogga. Waxay kaloo waxtar u yeelankartaa ilaaliye ahaan waxyeelada nidaamka dareemayaasha jirka sababto ah cudurka loo yaqaan 'Lyme disease' sidoo kale wuxuu ka ilaalin karaa qulqulka maskaxda.

Qiyaasta Lithium orotate

Sababtoo ah kor u qaadista bioavailability ee lithium orotate, qiyaasta daaweynta ayaa ka yar qaababka loo qoro lithium. Faa'iidooyin badan ayaa u leh qaadashada lithium orotate qiyaasta hoose.

Qiyaasta caadiga ah waa inta u dhaxaysa shan ilaa 20 mg. Waxay sidoo kale ku siin karaan qaab dareere ah, khaas ahaan qiyaastii 250mcg. Qiyaastaan, ma ahan sun.

Xaaladaha niyadjabka daran, qiyaasta daaweynta ee lithium orotate waa 150 mg / maalintii. Tani waxaa la barbar dhigaa 900-1800 mg oo foomamka dawooyinka la qoro ah. Qiyaasta dawadan ee lithium orotate, ma jiraan falcelin xun oo dhinaca lithium ah isla markaana uma baahna kormeer cabbiraada dhiiga dhiiga.

Isticmaalka Lithium orotate / codsiyada

Sida cunto dheeri ah, Lithium orotate waxaa loo isticmaali karaa qiyaaso yar yar si loogu daaweeyo xaaladaha sida niyadjabka manic, khamriga, ADHD iyo ADD, niyadjabka, gardarada, PTSD, Alzheimer Cudurka iyo guud ahaan maareynta walaaca.

Daawooyinka kale, lithium orotate waxaa loo isticmaali karaa daaweynta iyo ka hortagga xaaladaha soo socda:

Walaaca

Laba-cirifoodka

Madax xanuun

Depression

gulukooma

hurdo

Dhanjaf

Cudurka Parkinson

Dhibaatada walaaca ka dhasha khalkhalka ka dambeeya

Intaa waxaa dheer, lithium orotate ayaa sidoo kale loo isticmaalaa in lagu hagaajiyo xusuusta, yareynta xanuunka iyo yareynta walbahaarka.

Cilladaha Lithium orotate

Intaa waxaa dheer dheefaha kor ku xusan, lithium orotate sidoo kale waxay ukeeneysaa waxoogaa saameyn dhinaca jirka ah, oo ah cad:

Warbixin 2007 oo lagu daabacay joornaalka 'Journal of Medical Toxicology' ayaa ka digaya in lithium orotate ay lahaan karto qaar ka mid ah waxyeelada sunta ah, isticmaalka daba dheeraada ee loo yaqaan 'lihium orotate' ayaa sababi kara lallabo iyo gariir. Marka lala socdo lallabbo iyo matag, waxay sidoo kale sababaan wadnaha wadnaha iyo dhibaatooyinka maskaxda. Waxaa sidoo kale jira walaac laga qabo in isticmaalka lithium orotate uu hoos u dhigo shaqada kalyaha.

Sidoo kale, lithium orotate waxay yeelan kartaa xoogaa isdhaafsi ah daawooyinka kale. sida ACE inhibitors, anticonvulsants, antidepressants, caloosha kaalshiyamka kaalshiyamka ah, dextromethorphan, loop diuretics, meperidine, methyldopa, iyo monoamine oxidase inhibitors (MAOIs), iwm.

Adoo tixgelinaya halista caafimaad ee laxiriirta sunta, waxay ubaahantahay inaad dhiig-baadhis ku samayso waqti si aad u hubiso in heerarka sunta ah ee dawada aan la gaarin markii la isticmaalo lithium orotate.

Tixraaca:

  • ACOG Gudiga Xusuus-qorka Caadada — Obstetrics. Buug-yaraha Xirfadda ACOG: Tilmaamaha maareynta bukaan-eegtada ee takhtarka dhalmada iyo takhtarka dhalmada lambarka 92, Abriil 2008 (wuxuu beddeley nambarka warbixinta 87, Noofembar 2007). Isticmaalka dawooyinka maskaxda markay uurka leeyihiin iyo naas nuujinta. Obstet Gynecol. 2008; 111: 1001-1020.18378767.
  • Balon R. Khataraha suurtagalka ah ee "dheeri nafaqada" lithium orotate. Ann Clin Maskaxda. 2013; 25 (1): 71.23376874.
  • Barkins R. Lithium-ka hooseeya iyo saamaynta taageeradiisa caafimaad leh. Nutr Muuqaal. 2016; 39 (3): 32-34.
  • Heim W, Oelschläger H, Kreuter J, Müller-Oerlinghausen B. Xoreynta lithium oo laga sii daayay sii deynteeda. Isbarbar dhigga toddobada nooc ee diiwaangashan. Farmashiyaha. 1994; 27 (1): 27-31.8159780.
  • Nieper, Hans Alfred (1973), “Codsiyada kiliinikada ee lithium orotate. Daraasad labo sano ah ”, Agressologie, 14 (6): 407–11, PMID 4607169.
  • Gong R, Wang P, Dworkin L. Waxa aan u baahan nahay inaan ka ogaano saameynta lithium kelyaha. Anigu waxaan ahay J Jilio Renal Physiol. 2016; 311 (6): F1168-F1171.27122541.

U DIYAAR-GARASHADA iyo kala-tagga:

Qalabkan waxaa loo iibiyaa Adeegsiga Cilmi-baarista Kaliya. Shuruuda Iibka ayaa la Codeynayaa. Loogu talagalay Isticmaalidda Aadanaha, ama Daawooyinka, Caafimaadka Xoolaha, ama Isticmaalka Guryaha.