NADP cusbada cusbada (24292-60-2)

March 15, 2020

Nicotinamide adenine dinucleotide phosphate (NADP +) waa cofactor loo isticmaalo falcelinta anabolic. β-Nicotinamide adenine ……

 


Status: Wax soosaarka Mass
Unugga: 25kg / Drum

 

NADP cusbada cusbada (24292-60-2) video

-Nicotinamide adenine dinocleotide fosfow cusbada cusbada (NADP cusbada disodium) Smamnuucista

Product Name -Nicotinamide adenine dinucleotide fosfow cusbo disodium cusbo (NADP cusbo cusbada)
Magaca Kiimikada NADP Disodium; Nadide foshate disodium; NADP; β-NADP; Triphosphopyridine nucleotide disodium salt;
CAS Number 24292-60-2
InChikey UNRRSQIQTVFDLS-WUEGHLCSSA-L
dhoolla caddayntaada C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O)C(=O)N.[Na+].[Na+]
Formula kelli C21H26N7Na2O17P3
Miisaanka kelli 787.37
Monoisotopic Mass 787.039342 g / mol
Dhibicda Biyaha 175-178 ° C
Color Yellow
Skulayl daran -20 ° C
Biyaha  milmi > 50 g / L
Codsiga Coenzyme ee aerobic iyo oxidations anaerobic

 

Waa maxay β-Nicotinamide adenine dinucleotide phosphate cusbada disodium (NADP cusbada cusbada)?

Nicotinamide adenine dinucleotide phosphate (NADP +) waa cofactor loo isticmaalo falcelinta anabolic. β-Nicotinamide adenine dinucleotide fosfatedium cusbo waa cusbo kujirta NADP +, waa coenzyme lagama maarmaanka u ah halsanka khamriga ee gulukooska iyo oksidheid okidjiid ee walxaha kale. Waxayna si ballaaran ugu dhacdaa unugyada nool, gaar ahaan beerka.

Nicotinamide adenine dinucleotide phosphate (NADP) iyo NADPH waxay sameeyaan labo redox. NADPH / NADP saamiga ayaa nidaaminaya awoodda dib-u-soo-celinta intracellular, gaar ahaan jawaabta anaerobic, taas oo saamayneysa jawaabta dheef-shiidka ee jirka. Tusaalooyinku waa lipid iyo isku-darka aasaaska aashitada. NADP sidoo kale waa lammaane coenzyme ah oo ku jira nidaamyada kaladuwan ee loo yaqaan 'cytochrome P450 cytochrome' iyo hababka falcelinta oxidase / reductase sida nidaamka loo yaqaan 'thioredoxin reductase / thioredoxin system'.

NADPH waxay bixisaa dhimista u dhigma ficil celinta biosynthetic waxayna bixisaa saameyn redox ah si looga hortago sunta noocyada oksijiinta firfircoon (ROS), iyadoo dib loo soo nooleeyo guluf-ka (GSH). Waxaa sidoo kale loo isticmaalaa wadiiqooyinka anabolic-ka sida kolestaroolka isku-darka iyo dufanka xayrta ee loo yaqaan 'Chain kordhin'.

Intaa waxaa sii dheer, Nidaamka NADPH wuxuu sidoo kale mas'uul ka yahay abuurista xag-jiryo bilaash ah unugyada ka hortagga iyada oo loo marayo NADPH oxidase. Kuwaas xag-jirka ah ee bilaashka ah waxaa loo isticmaalaa in lagu baabi'iyo cudurada ku dhaca hab la yiraahdo neefsashada oo ku dhaca. Waa yareyn u dhiganta isha aashkadda cytochrome P450 hydroxylated aromatics, steroids, khamriga, iyo daroogada.

 

Codsiga ee β-Nicotinamide adenine dinucleotide fosfow cusbada disodium

Nicotinamide adenine dinucleotide phosphate (NADP) iyo NADPH waxay sameeyaan labo redox. NADP / NADPH waa coenzyme oo taageerta falcelinta redox iyada oo loo marayo gaadiidka elektarooniga ah ee adeegyo fara badan, gaar ahaan falcelinta anaerobic sida lipid iyo synthesis-ka nucleic acid. NADP / NADPH waa lamaane coenzyme ah oo ku jira nidaamyo kala duwan oo cytochrome P450 ah iyo hababka falgalka oxidase / reductase, sida nidaamka thioredoxin reductase / thioredoxin.

Enzymesyada kale ee u isticmaala NADP sidii coenzyme waa: Alcohol dehydrogenase: NADP ku tiirsan; Aromatic ADH: NADP ku tiirsan; Ferredoxin-NADP reductase; L-Fucose dehydrogenase; Gabase; Galactose-1-phosphate uridyl gudbinta; Gulukoos dehydrogenase; L-Glutamic dehydrogenase; Glycerol dehydrogenase: NADP gaar ah; Isocitric dehydrogenase; Enzymesyada malic; 5,10-Methylenetetrahydrofolate dehydrogenase; 6-Phosphogluconate dehydrogenase iyo Succinic semialdehyde dehydrogenase.

 

Tixraaca:

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