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Dareeraha Riv Flibanserin HCL (147359-76-0)

Dareeraha Fibbistersin Hydrochloride, oo lagu iibiyo magaca ganacsiga Addyi, waa dawo la oggolaaday daaweynta ...


Status: Wax soosaarka Mass
Unugga: 25kg / Drum
Capacity: 1250kg / bishii

Description

Daawada Raw Flibanserin HCL (147359-76-0)

Root Flibanserin HCL budada (147359-76-0) Smamnuucista

Product Name Duufka dareeraha ee Flibanserin hydrochloride
Magaca Kiimikada UNII-96XTC36K1B, 96XTC36K1B
brand NAme Addyi
Fasalka Daroogada Noocyo dhexdhexaad ah serotonin agonist (MSAA)
CAS Number 147359-76-0
InChikey XGAGFLQFMFCIHZ-UHFFFAOYSA-N
Molecular Formula C20H22ClF3N4O
Molecular Wsideed 426.8630896
Monoisotopic Mass 426.143 g / mol
barafku Psaliid > 225 ° C (dec.)
Fdib u soo celinta Psaliid Taariikhda lama heli karo
Biological Life-Life saacadood 11
Color White adag
SOlubility DMSO (Hoos Joog), Methanol (Gaar ah)
Storage Temperature Heerkulka qolka
Application Horumarinta daaweynta xanuunka rabitaanka galmada ee galmada ee dumarka.

Raw Flibanserin HCL budada (147359-76-0) Sharaxaad

Flibanserin hydrochloride waa daroogada ugu horeysa ee loo oggol yahay xanuunka rabitaanka galmada ee galmada (HSDD) ee haweenka uurka leh ee FDA in August 2015. Waxaa asal ahaan lagu hormariyay daawada antidepressant by Boehringer Ingelheim, laakiin waxay muujisay inaysan lahayn waxtarka tijaabooyinka waxaana lagu hormariyay daroogada khalkhalka galmada ee hodanka ah ee loo yaqaan Sprout Pharmaceuticals. Qalabka ficil-ka ee Flibanserin waxaa loo aanaynayaa xajmintiisa sare ee 5-HTA1 iyo 5-HTA2, oo muujinaya dhaqdhaqaaqa agonist on 5-HTA1 iyo antagonist on 5-HTA2, taasoo keentay hoos u dhaca serotonin ee maskaxda iyo sidoo kale saameynta sii kordhaya norepinephrine iyo dopamine neurotransmitters.

Xakamaynta dareeraha (Flasinserin hydrochloride) (147359-76-0) Habka Wax-qabadka

Flibanserin hydrochloride waxay ka shaqaysaa saddex kiimikood oo muhiim ah oo ah kiimikada maskaxda: dopamine, norepinephrine, iyo serotonin. Kiimikooyinkaas waa kuwa neurotransmitters. Waxay mas'uul ka yihiin inay diraan calaamadaha u dhexeeya maskaxda iyo qaybaha kale ee jidhka iyada oo loo marayo nidaamka dareenka.

Dopamine iyo norepinephrine waxay ku lug leeyihiin jacaylka galmada. Si kastaba ha ahaatee, serotonin waxuu ka qaybqaataa galmada la xakameyn karo waxaana laga yaabaa in uu nadiifiyo galmada. Waxaa la rumeysan yahay in haddii kiimikooyinkan ay ka baxaan dheelitir - haddii dopamine iyo norepinephrine aad u hooseeyo iyo / ama serotonin heerkoodu aad u sarreeyo - haweeney waxay dareemeysaa rabitaan yar oo galmo ah.

Flibanserin hydrochloride waxay u shaqaysaa kor u kaca heerarka dopamin iyo norepinephrine halka hoos u dhigidda heerarka serotonin. Sidan oo kale, kiimikooyin gacan ka geysanaya dhiirigelinta rabitaanka galmada ayaa kordhay oo midkastaa uu xakameyn karo rabitaankiisa ayaa hoos u dhacaya.

Isticmaalka budada Raw Flibanserin HCL (147359-76-0)

Flibanserin hydrochloride waa 5-HT1A agonist iyo 5-HT2A antagonist kaasoo loogu talagalay daaweynta qalalaasaha jinsiga ee rabitaanka galmada dumarka (1,2).

Foomka lagu taliyay ee loo yaqaan "Flibanserin HCL" (147359-76-0)

100 mg afka ah hal mar hal maalin maalintii waqtiga hurdada

Muddada daaweynta: Daawadan waa in la joojiyaa ka dib marka ay toddobaadyadooda XNUM haddii bukaanku aanu soo sheegin ciladaha soo kabashada.

Faallooyinka: Daawadani looma sheegin si kor loogu qaado waxqabadka galmada, loomana tilmaamayo daaweynta haweenka postmenopausal ama ragga.

Saameynaha ka yimaada budada dufan ee Flibanserin hydrochloride (147359-76-0)

Dhacdooyinka khatarta ah waxay ku badan yihiin dumarka qaata nacasta. Inta badan dhacdooyinka qaska ah waxay ahaayeen kuwo fudud oo dhexdhexaad ah. Dhacdooyinka ugu badan ee lagu soo warramey waxaa ka mid ahaa dawakhaad, lallabbo, daal, hurdo, iyo hurdo la'aan.

Cabitaanka khamriga inta uu ku jiro flibanserin waxay keeni kartaa cadaadis dhiig oo aad u hooseeya (cadaadiska dhiigga oo hoos u dhaca taasoo keentay calaamado ka dib markii muraayadaha khamriga ee 2 ay ka dhaceen 17%).

U DIYAAR-GARASHADA iyo kala-tagga:

Qalabkan waxaa loo iibiyaa Adeegsiga Cilmi-baarista Kaliya. Shuruuda Iibka ayaa la Codeynayaa. Loogu talagalay Isticmaalidda Aadanaha, ama Daawooyinka, Caafimaadka Xoolaha, ama Isticmaalka Guryaha.


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Shangke Kiimikadu waa shirkad tayo sare leh oo ku takhasusay dhexdhexaadinta firfircoon ee daawada (APIs). Si loo xakameeyo tayada inta lagu jiro wax soo saarka, tiro badan oo xirfadlayaal khibrad leh, qalab wax soosaaraya iyo shaybaarrada ayaa ugu muhiimsan.

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