NADH 2Na (606-68-8)

March 15, 2020
SKU: 129311-55-3
5.00 ka mid ah 5 ku saleysan 1 macaamiisha rating

NADH waa nooc nzyotinamide adenine dinucleotide (NAD) enzyme, nooc coenzyme ah oo ka shaqeeya xarunta iyo fiitamiin B3 ……….


Status: Wax soosaarka Mass
Isuduwis iyo Haboonaanta La Isticmaali karo
Capacity: 1277kg / bishii

NADH 2Na (606-68-8) fiidiyow


Beta-Nicotinamide adenine dinocleotide cusbada disodium (NADH 2Na) Faahfaahin

Product Name Beta-Nicotinamide adenine cusbada disodium cusbada (NADH 2Na)
Magaca Kiimikada NADH (cusbada disodium); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Salt; Nicotinamide adenine dinucleotide, oo la yareeyay;
CAS Number 606-68-8
InChikey QRGNQKGQENGQSE-WUEGHLCSSA-L
dhoolla caddayntaada C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Formula kelli C21H27N7Na2O14P2
Miisaanka kelli 709.4
Monoisotopic Mass 709.088661 g / mol
Dhibicda Biyaha 140-142 ℃
Color Yellow
Skulayl daran 2-8 ℃
milmi H2O: 50 mg / mL, u cad ilaa cad cad, jaalle ah
Codsiga Daawada; cuntada iyo kaabista nafaqada leh;

Waa maxay Beta-Nicotinamide adenine dinucleotide cusbada disodium (NADH 2Na)?

NADH waa nooc nzyotinamide adenine dinucleotide (NAD) enzyme, nooc coenzyme ah oo ka shaqeeya xarunta iyo fitamiin B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium Salt, oo la yareeyay, oo sidoo kale loo yaqaan Nicotinamide adenine dinucleotide, waa coenzyme falcelinta redox. Hawlaheeda sidii dib-u-cusboonaysiinta ku-deeqa elektaroniga ee geedi socodka catabolic oo ay ku jiraan glycolysis, β-oxidation iyo wareegga citric acid (Wareegga Krebs, wareegga TCA). Cusbada dishaum-ka ee NADH waxay sidoo kale kaqeybqaadataa dhacdooyinka calaamadaynta unugyada, tusaale ahaan bedelida polymerases poly (ADP-ribose) (PARPs) inta lagu jiro jawaabta waxyeelada DNA. Sida cusbada xididka ee NADH, waxaa loo isticmaalaa cunnooyinka iyo kaabista nafaqada ah ee daaweynta daweynta cudurka Parkinson, daalka daalka daran, cudurka Alzheimer iyo cudurada wadnaha.

Beta-Nicotinamide adenine dinucleotide cusbada disodium (NADH 2Na)

Sida coenzyme-ka loo yaqaan 'oxidoreductases', cusbada dishaum ee NADH waxay door muhiim ah ka ciyaaraysaa soosaarka tamarta jirka.

- Cusbada budada budada ee NADH waxay horseedi kartaa caddeyn maskaxeed oo wanaagsan, feejignaan, u fiirsasho, iyo xusuusta. Waxay kordhin kartaa nusqaanka maskaxda waxayna kordhin kartaa niyadda. Waxay kordhin kartaa heerarka tamarta ee jirka waxayna wanaajisaa dheef-shiid kiimikaadka, awoodda maskaxda iyo adkeysiga.

- Caawi dadka qaba diiqadda kiliinikada, dhiig karka ama kolestarool sare;

- Hagaajinta waxqabadka ciyaaraha fudud;

- Dib u dhig hannaanka gabowga una ilaali daacadnimada unugyada neerfaha si ay u taageeraan nidaamka neerfaha;

- Waxaa laga yaabaa inay daaweyso cudurka Parkinson, inay hagaajiso shaqada neurotransmitters ee maskaxda bukaanka qaba cudurka Parkinson, yareyn karto naafonimada jirka iyo baahiyaha daroogada;

- Daaweynta syndrome daalka daba-dheer (CFS), cudurka Alzheimers iyo cudurka wadnaha;

- Kahortag waxyeelada dawooyinka AIDS ee loo yaqaan zidovudine (AZT);

- Ka soo horjeedda saameynta aalkolada ee beerka;

- Daalka diyaaradda

Beta-Nicotinamide adenine cusbada disodium cusbada (NADH 2Na) waxyeelooyinka:

Waqtiga xaadirka, cusbada budada NADH waxay umuuqataa amaan dadka badidooda markii loo isticmaalo si ku haboon iyo waqti gaaban, ilaa 12 todobaad. Dadka badankood ma la kulmaan wax dhibaato ah marka ay qaadanayaan qaddarka lagu taliyay maalin kasta, oo ah 10 mg.

Si kastaba ha noqotee, ma jiro xog ku filan oo ku saabsan isticmaalka cusbada dishaum-ka ee NADH inta lagu jiro uurka iyo naas-nuujinta, sidaa darteed waa inay ku ekaadaan dhinaca nabdoon oo ay ka fogaadaan isticmaalkooda.

Tixraaca:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - hab cusub oo lagu daweeyo cudurka Parkinson. Isbarbardhigga codsi afka ah iyo mid bilow ah. Acta Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, ed. Tusmada 'Merck Index'. 12aad ed. Xarunta Whitehouse, NJ: Merck & Co., Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Hoos u dhaca B-nicotinamide adenine dinucleotide (NADH) wuxuu saameeyaa cadaadiska dhiigga, lipid peroxidation, iyo muuqaalka lipid ee jiirka hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Hoos u dhaca B-nicotinamide adenine dinucleotide (NADH) wuxuu saameeyaa cadaadiska dhiigga, lipid peroxidation, iyo muuqaalka lipid ee jiirka hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Afka 'coenzyme Q10' iyo kabitaanka NADH ee miyey kor u qaadaysaa daalka iyo cabirrada bayoolaji ee astaamaha daalka dabadheer? Calaamadaha Antioxid Redox 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Daaweynta cudurka Parkinson's NADH. Acta Neurol Scand 1994; 90: 345-7.

U DIYAAR-GARASHADA iyo kala-tagga:

Qalabkan waxaa loo iibiyaa Adeegsiga Cilmi-baarista Kaliya. Shuruuda Iibka ayaa la Codeynayaa. Loogu talagalay Isticmaalidda Aadanaha, ama Daawooyinka, Caafimaadka Xoolaha, ama Isticmaalka Guryaha.