NADH 2Na (606-68-8)

March 15, 2020

NADH waa nooc ka mid ah nicotinamide adenine dinucleotide (NAD) enzyme, oo ah nooc firfircoon oo coenzyme ah oo ka kooban dhisme iyo fiitamiin B3 ……….

 


Status: Wax soosaarka Mass
Isuduwis iyo Haboonaanta La Isticmaali karo
Capacity: 1277kg / bishii

NADH 2Na (606-68-8) fiidiyow

Beta-Nicotinamide adenine dinocleotide cusbada disodium (NADH 2Na) Faahfaahin

Product Name Beta-Nicotinamide adenine cusbada disodium cusbada (NADH 2Na)
Magaca Kiimikada NADH (cusbada disodium); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Salt; Nicotinamide adenine dinucleotide, oo la yareeyay;
CAS Number 606-68-8
InChikey QRGNQKGQENGQSE-WUEGHLCSSA-L
dhoolla caddayntaada C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Formula kelli C21H27N7Na2O14P2
Miisaanka kelli 709.4
Monoisotopic Mass 709.088661 g / mol
Dhibicda Biyaha 140-142 ℃
Color Yellow
Skulayl daran 2-8 ℃
milmi H2O: 50 mg / mL, u cad ilaa cad cad, jaalle ah
Codsiga Daawada; cuntada iyo kaabista nafaqada leh;

 

Waa maxay Beta-Nicotinamide adenine dinucleotide cusbada disodium (NADH 2Na)?

NADH waa nooc ka mid ah nicotinamide adenine dinucleotide (NAD) enzyme, oo ah nooc firfircoon oo coenzyme ah oo ka kooban dhisme iyo fiitamiin B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium Salt, hoos loo dhigay, sidoo kale loo yaqaan Nicotinamide adenine dinucleotide, waa coenzyme falcelin redox. Hawlaheeda sida dib-u-cusbooneysiiyaha deeq-bixiyeha elektaroonigga ah ee hababka catabolic oo ay ku jiraan glycolysis, β-oxidation iyo wareegga acid-ka (wareegga Krebs, wareegga TCA). NADH saltdium cusbada ayaa sidoo kale kaqeybqaata dhacdooyinka tilmaamaya unugyada, tusaale ahaan sida substrate-ka poly (ADP-ribose) polymerases (PARPs) inta lagu gudajiro jawaabta dhaawaca DNA. Maaddaama ay tahay cusbada dhiigga 'NADH', waxaa loo isticmaalaa cuntada iyo nafaqeynta nafaqada ee daaweynta cudurka Parkinson, cilladda daalka daba dheeraada, cudurka Alzheimer iyo cudurrada wadnaha iyo xididdada dhiigga.

 

Beta-Nicotinamide adenine dinucleotide cusbada disodium (NADH 2Na)

Maaddaama loo yaqaan 'coenzyme of oxidoreductases', NADH saltdium cusbo ayaa door muhiim ah ka ciyaara soosaarka tamarta jirka.

- Cusbada 'NADH sibdium' waxay u horseedi kartaa hufnaan maskaxeed, feejignaan, feejignaan, iyo xusuus. Waxay kordhin kartaa miyir-qabka maskaxda waxayna kordhin kartaa niyadda. Waxay kordhin kartaa heerarka tamarta ee jirka waxayna hagaajin kartaa dheef-shiid kiimikaadka, awoodda maskaxda iyo adkeysiga.

- Ka caawi dadka qaba niyad-jabka caafimaad, dhiig-karka ama kolestaroolka sare;

- Hagaajinta waxqabadka cayaaraha;

- Daahitaanka gabowga oo dib loo dhigo lana ilaaliyo sharafta unugyada neerfaha si loo taageero nidaamka neerfaha;

- Waxaa laga yaabaa in lagu daaweeyo cudurka Parkinson, wuxuu hagaajiyaa shaqada neerfaha gudbiya maskaxda ee bukaanka qaba cudurka Parkinson, wuxuu yareeyaa naafonimada jireed iyo baahiyaha daroogada;

- Daaweynta cilladda daalka daba dheeraatay (CFS), cudurka Alzheimers iyo cudurrada wadnaha iyo xididdada dhiigga;

- Ka ilaali waxyeelada daawada AIDS-ka loo yaqaan zidovudine (AZT);

- Ka soo horjeed saamaynta khamrigu ku leeyahay beerka;

- Daalka diyaaradda

 

Beta-Nicotinamide adenine cusbada disodium cusbada (NADH 2Na) waxyeelooyinka:

Waqtiga xaadirka, cusbada budada NADH waxay umuuqataa amaan dadka badidooda markii loo isticmaalo si ku haboon iyo waqti gaaban, ilaa 12 todobaad. Dadka badankood ma la kulmaan wax dhibaato ah marka ay qaadanayaan qaddarka lagu taliyay maalin kasta, oo ah 10 mg.

Si kastaba ha noqotee, ma jiro xog ku filan oo ku saabsan isticmaalka cusbada dishaum-ka ee NADH inta lagu jiro uurka iyo naas-nuujinta, sidaa darteed waa inay ku ekaadaan dhinaca nabdoon oo ay ka fogaadaan isticmaalkooda.

 

Tixraaca:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - waa hab daaweyn oo cusub oo lagu daweeyo cudurka Parkinson. Isbarbardhiga arjiga af iyo waalidba. Qalabka 'Neuroa Scand Suppl' 1993; 146: 32-5.
  • Budavari S, ed. Tilmaanta 'Merck Index' 12aad ed. Xarunta Aqalka Cad, NJ: Merck & Co., Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Hoos u dhaca B-nicotinamide adenine dinucleotide (NADH) wuxuu saameeyaa cadaadiska dhiigga, lipid peroxidation, iyo muuqaalka lipid ee jiirka hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Hoos u dhaca B-nicotinamide adenine dinucleotide (NADH) wuxuu saameeyaa cadaadiska dhiigga, lipid peroxidation, iyo muuqaalka lipid ee jiirka hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Afka 'coenzyme Q10' iyo kabitaanka NADH ee miyey kor u qaadaysaa daalka iyo cabirrada bayoolaji ee astaamaha daalka dabadheer? Calaamadaha Antioxid Redox 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Daaweynta cudurka Parkinson ee NADH. Acta Neurol Scand 1994; 90: 345-7.