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Xavi Nikotinamide Mononucleotide (NMN) budada (1094-61-7)

Root Nicotinamide Mononucleotide (NMN) budada ayaa xakameynaya miisaanka jidhka ee da'da ku xiran


Status: Wax soosaarka Mass
Unugga: 25kg / Drum
Capacity: 1370kg / bishii

Description

Qalabka Nikotinamide Mononucleotide (NMN) budada (1094-61-7) video

Root Nicotinamide Mononucleotide (NMN) budada (1094-61-7)

Root Nicotinamide Mononucleotide budada ("NMN" iyo "β-NMN") waa nukleotide oo laga helo ribose iyo nicotinamide. Sida nicotinamide riboside, NMN waa nooc ka mid ah niacin, bini-aadanna waxay leeyihiin enzymes oo isticmaali kara NMN si loo abuuro nicotinamide adenine dinucleotide (NADH).

Sababtoo ah NADH waa cofactor for geedi socodka gudaha mitochondria, for sirtuins, iyo for PARP, NMN ayaa lagu baranayaa qaababka xayawaanka sida sheyga neuroprotective iyo wakiilka gabowga. Shirkadaha dheeriga ah ee cuntada lagu iibiyo waxay si ba'an u iibiyeen alaabooyinka NMN ee sheeganaya faa'iidooyinkaas, inkasta oo aanay jirin daraasad kiliin ah oo bini'aadan ah oo weli la daabacay.

Macmacaanka Nicotinamide Mononucleotide (NMN) Root (1094-61-7) Qalabka

Product Name Root Nicotinamide Mononucleotide (NMN) budada
Magaca Kiimikada Beta-nicotinamide ribose monophosphate; Root Nicotinamide Mononucleotide budada; AC1Q6RVF; AC1L23AN; NMN (+); SCHEMBL6858129
brand NAme Mirailabo
Fasalka Daroogada Kaalmada cuntada
CAS Number 1094-61-7
InChikey DAYLJWODMCOQEW-TURQNECASA-N
Molecular Formula C11H15N2O8P
Molecular Wsideed 334.22
Monoisotopic Mass 335.229 g / mol
barafku Psaliid > 96 ° C
Fdib u soo celinta Psaliid Taariikhda lama heli karo
Biological Life-Life Sidaa darteed, sida lagu muujiyey Sawirka 3, nicotinamide wuxuu ka lumay dhiigga noloshiisa nus saacadaha 5.3, halka nolosha nuska ah ee nicotinic acid ahaa saacad 1.1.
Color Caddaan cad oo budada ah
SOlubility Methanol (Si Fiican), Biyaha (Si Fiican)
Storage Temperature Hygroscopic, -20˚C Qaboojiyaha, Under In Atmosphere
Application Si loo ciyaaro kaalinta nolosha dheeraadka ah iyo daaweynta cudurka macaanka

Root Nicotinamide Mononucleotide (NMN) budada (1094-61-7) Tafaasiisha

Root Nicotinamide Mononucleotide budada ("NMN" iyo "β-NMN") waa nukleotide oo laga helo ribose iyo nicotinamide. Sida nicotinamide riboside, NMN waa nooc ka mid ah niacin, bini-aadanna waxay leeyihiin enzymes oo isticmaali kara NMN si loo abuuro nicotinamide adenine dinucleotide (NADH).

Cilmi-baaris cusub ayaa soo jeedinaysa in NMN ay dib u soo celin karto dheef-shiid kiimikaad, oo leh waxyaabo horey u ah gabow gabowga. Waxyaabaha dabiiciga ah ee ku dhaca jirka, NMN (β-Nicotinamide mononucleotide) waxay muhiim u tahay beddelidda nafaqooyinka tamarta. Kudarinta NMN oo qayb ka ah nidaamka maalinlaha ah ayaa bixin kara korriin tamareed, ilaalin habka gabowga, iyo khatarta hoos u dhaca dhibaatooyinka wadnaha. NMN waa cofactor oo ku jira fal-celinta redox-ka, geedi socodka muhiim u ah hawsha dheef-shiid kiimikaad ee sameynta ATP maaddada tamarta sare. NMN waxaa ku jira maadada firfircoon ee Sirtuin kaas oo kor u qaada saxarada dhererka iyo mudnaanta.

Isticmaalka Nikotinamide Mononucleotide (NMN) budada (1094-61-7)

  1. Nikotinamide mononucleotide ee unugyada aadanaha ayaa door muhiim ah ka ciyaara abuurista tamarta, waxay ku lug leedahay nacotinamide adenine dinucleotide, isugeynta unugyada tamarta ee muhiimka ah coenzyme), oo loo isticmaalo da 'anti-aging, sonkorta dhiiga iyo waxyaabaha kale ee daryeelka caafimaadka.
  2. Nikotinamide Mononucleotide waa faytamiin biyo ah, Qalabkuna waa budada kiniinka cadceedda ah, ur aan lahayn ama ku dhawaad ​​ur aan lahayn, qadhaadh dhadhan, si xor ah u foori kara biyaha ama ethanol, oo lagu kala diri karo glycerin.
  3. Nikotinamide Mononucleotidepowderis si sahlan ayey u qaadataa afka, waxaana si ballaaran loogu qaybin karaa jirka, dheef-shiid kiimikaad sarreeya ama prototype si dhakhso ah uga saara kaadida. Nicotinamide waa qayb ka mid ah coenzyme I iyo coenzyme II ayaa kaalin ka qaata bixinta hydrogen soo saarista gaaska noolaha ee noolaha hawada ee biological oxidation, wuxuu kor u qaadi karaa hababka qoyaanka oxidation iyo qaabka dheef-shiid kiimikaadka, haynta unugyada caadiga ah (gaar ahaan maqaarka, habka dheef-shiidka iyo habdhiska dareenka).

Intaa waxaa dheer, nicotinamide wuxuu leeyahay ka hortagga iyo daaweynta qalabka wadnaha, nudaha wadnaha, nicotinamide, wuxuu si weyn u wanaajin karaa heerka garaaca wadnaha iyo atrioventricular taasoo sababtay verapamil.

Faa'iidooyinka ee Nicotinamide Mononucleotide (NMN) budada (1094-61-7)

  • NMN waxay xireysaa dheef-shiid kiimikaadka - NAD + wuxuu ka caawiyaa sidii loo burburin lahaa cuntada sida sonkorta tamarta.
  • Waxay dhiirrigelisaa Hawsha caafimaadka maskaxda iyo wadnaha.
  • Dayactiridda DNA-da Nadiifinta - NAD + waxaa loo isticmaalaa in lagu hagaajiyo xaddiga DNA-ga ee jabay.
  • SIRTUIN Activator - NAD + ayaa looga baahan yahay hiddaheena mudada dheer ee shaqada.
  • NMN waa xaruntu isticmaasho Harvard Scientists si ay u calaamadiso calaamadaha da'da gaboobay ee jiirarka bilaabay degdegga ah ee NAD supplements.
  • Daaweynta NMN waxay ka hortageysaa CICH-ku-dillaacda dhaawaca maskaxda
  • NMN Nidaamyada Daaweynta Daaweynta Naafada Garashada
  • Nikotinamide mononucleotide wuxuu joojiyaa dhaqdhaqaaqa JNK si loo ciribtiro cudurka Alzheimer
  • NMN waxay soo celin kartaa garashada jiirka jadeecada

Nooc lagu daaweynayo Nikotinamide Mononucleotide (NMN) budada (1094-61-7) Qiyaasta

Qiyaasta guud ee lagu taliyey ee loo yaqaan 'Nicotinamide Mononucleotide budada waa meel kasta oo u dhaxaysa 250 - 1500 mg maalintii.

NMN si dhakhso ah ayey u neefsataa waxayna leedahay nolol yar oo gaaban, sidaa daraadeed si loo ilaaliyo NAD + heerarka ugu badan ee suurtogalka ah waxaa lagula talinayaa in la qaato mid ka mid ah xayawaanka mg 125 ee soo kicinta iyo mid kale galinka dambe haddii uu qaato mg XMUMX maalintii.

Dhibaatooyinka ay keento ee Nicotinamide Mononucleotide (NMN) budada (1094-61-7)

Inkastoo budada loo yaqaan 'Nikotinamide mononucleotide (NMN) budhcad-badeeddu waa mid cusub, oo cilmi-baarisuna socoto, daraasadihii la sameeyey ilaa iyo hadda waxay muujisay in ay tahay mid aad u ammaan badan oo aan sun ahayn.

Dhibaatooyinka kale waa dhif, laakiin cuncun, madax-wareer, dhidid, iyo lallabo ayaa laga soo sheegay xaaladaha qaarkood.

U DIYAAR-GARASHADA iyo kala-tagga:

Qalabkan waxaa loo iibiyaa Adeegsiga Cilmi-baarista Kaliya. Shuruuda Iibka ayaa la Codeynayaa. Loogu talagalay Isticmaalidda Aadanaha, ama Daawooyinka, Caafimaadka Xoolaha, ama Isticmaalka Guryaha.


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Tixraacyada iyo xaashiyadaha alaabada

2019 Daawooyinka ugu Horeeya ee Daawooyinka: Nicotinamide Mononucleotide (NMN)

tixraacyada

  1. Mills, KF, Yoshino, J., Yoshida, S., iyo al. (2016). Maamulka Muddada-dheer ee Nicotinamide Mononucleotide wuxuu yareeyaa Dhibaatada Jirka ee Da'da Aasaasiga ah ee Mouse. Metabolism Cell.
  2. Yoshino, J., Mills, KF, Imai, SI, iyo Yoon, MJ (2011). Nikotinamide Mononucleotide, furaha NAD + Dhexdhexaad, Waxay daaweysaa Pathophysiology ee Cuntada Diabetes-da iyo Sonkorowga ee Mouse. Metabolism Cell.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., iyo Sadoshima, J. (2014). Nikotinamide Mononucleotide, oo ah dhexdhexaad ah NAD + Gaarsiisan, Ka ilaaliya wadnaha Ischemia iyo Reperfusion.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, iyo Morris, MJ (2016). Madaxa Madaxa Isbarbardhiga Daaweynta Muddada-gaaban ee NAD + horukaca Nicotinamide Mononucleotide (NMN) iyo lix Isbuuc oo Jimicsi ah oo ku yaalla Caanaha Naaska.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., et al. (2019) Slc12a8 waa gaadiidka Nicotinamide Mononucleotide. Metabolism Nature Nature.
  6. De Picciotto, NE, Mills, KF, Imai, S., Gano, LB, et al. (2016). Nikotinamide Mononucleotide wuxuu leexiyaa Vascular Qalitaanka iyo Cadaadiska Oxidative oo leh jiiraha gabowga.
  7. Yao, Z., Gao, Z., Yang, W., iyo Jia, P. (2017). Nikotinamide Mononucleotide wuxuu joojiyaa Cudurka Jnk si uu u noqdo Cudurka Alzheimer.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., et al. (2018). NAD + Kudhinta Noociya waxay ku xirantahay Noocyada muhiimka ah Alzheimer iyo DNA-ga Magdhawga Jawaabaha ee Qaabka cusub ee Mouse Mouse iyadoo la soo bandhigay Fududaynta Dayaca DNA.

Shangke Kiimikadu waa shirkad tayo sare leh oo ku takhasusay dhexdhexaadinta firfircoon ee daawada (APIs). Si loo xakameeyo tayada inta lagu jiro wax soo saarka, tiro badan oo xirfadlayaal khibrad leh, qalab wax soosaaraya iyo shaybaarrada ayaa ugu muhiimsan.

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